Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24196942 | 0.88 | PTGS2 (0.59) | MAPTLMNAKDM4EHPGDHTT | |
| SCHEMBL24196835 | 0.85 | CNR1 (0.46) | MAPTLMNAKDM4EHPGDHTT | |
| SCHEMBL30270541 | 0.85 | CNR1 (0.46) | MAPTLMNAKDM4EHPGDHTT | |
| SCHEMBL24196939 | 0.82 | HPGD (0.44) | MAPTLMNAKDM4EHPGDHTT | |
| SCHEMBL14247159 | 0.80 | RAB9A (0.84) | MAPTLMNARAB9AKMT2APOLB | |
| SCHEMBL13174673 | 0.78 | AKR1C3 (0.55) | MAPTLMNAKDM4EHPGDHTT | |
| SCHEMBL2730323 | 0.76 | ALDH1A1 (0.59) | MAPTLMNAKDM4EHPGDHTT | |
| SCHEMBL3846833 | 0.76 | HPGD (1.00) | MAPTLMNAKDM4EHPGDHTT | |
| SCHEMBL552251 | 0.75 | ALDH1A1 (0.44) | MAPTLMNAKDM4EHPGDHTT | |
| SCHEMBL20771586 | 0.74 | KDM4E (0.52) | MAPTLMNAKDM4EHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022008475-A1 | INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | UNIVERSITE CLAUDE BERNARD LYON 1 (FR) | 2022-01-13 | — | — | WO | disclosed |