Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26213974 | 0.81 | ACHE (0.47) | MAPTALDH1A1LMNAAPAF1MITF | |
| SCHEMBL24196826 | 0.81 | TOP1 (0.39) | MAPTALDH1A1LMNAAPAF1MITF | |
| SCHEMBL24196460 | 0.81 | HSP90AA1 (0.40) | MAPTALDH1A1LMNAAPAF1MITF | |
| SCHEMBL5461155 | 0.75 | ALDH1A1 (0.50) | MAPTALDH1A1LMNAAPAF1MITF | |
| SCHEMBL10370639 | 0.74 | ACHE (0.44) | MAPTALDH1A1LMNACA1CA2 | |
| SCHEMBL30269801 | 0.72 | CA1 (0.49) | ELANECA1CA2CA9CA12 | |
| SCHEMBL30270542 | 0.72 | ELANE (0.43) | MAPTALDH1A1LMNAAPAF1MITF | |
| SCHEMBL15932982 | 0.72 | CYP3A4 (0.41) | MAPTALDH1A1LMNAHTTCA1 | |
| SCHEMBL15929645 | 0.71 | ACHE (0.44) | MAPTALDH1A1LMNAHTTPKM | |
| SCHEMBL24196745 | 0.71 | CA1 (0.44) | MAPTALDH1A1LMNAAPAF1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022008475-A1 | INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | UNIVERSITE CLAUDE BERNARD LYON 1 (FR) | 2022-01-13 | — | — | WO | disclosed |