Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24156591 | 0.81 | MAPKAPK2 (0.34) | MAPKAPK2RPS6KA3CSNK2A1PLK3KDM4E | |
| SCHEMBL704132 | 0.75 | MAPKAPK2 (0.39) | MAPKAPK2RPS6KA3CSNK2A1PLK3KDM4E | |
| SCHEMBL24198524 | 0.74 | KDM4E (0.43) | TYMSKDM4EPKMALDH1A1MAPT | |
| SCHEMBL26222489 | 0.73 | EIF4A3 (0.42) | MAPKAPK2RPS6KA3CSNK2A1PLK3KDM4E | |
| SCHEMBL24156864 | 0.72 | MAPKAPK2 (0.37) | MAPKAPK2RPS6KA3CSNK2A1PLK3KDM4E | |
| SCHEMBL30218628 | 0.72 | MAPKAPK2 (0.37) | MAPKAPK2RPS6KA3CSNK2A1PLK3KDM4E | |
| SCHEMBL30548630 | 0.70 | HCAR1 (0.42) | — | |
| SCHEMBL626495 | 0.70 | GAA (0.33) | ADRA1AKDM4EALDH1A1MAPT | |
| SCHEMBL2825718 | 0.69 | DAO (0.47) | MAPKAPK2RPS6KA3CSNK2A1PLK3KDM4E | |
| SCHEMBL24157387 | 0.67 | PARP1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795158-B2 | Chemical compounds | ASTRAZENECA AB (SE) | 2023-10-24 | — | — | US | disclosed |
| US-20220009901-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2022-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11795158-B2 | Chemical compounds | CYP11B2, CYP11B1, CYP4B1 | ADRA1A 2923/4885TYMS 466/4885MAPKAPK2 2976/4885 |
| US-20220009901-A1 | CHEMICAL COMPOUNDS | CYP11B2, CYP11B1, CYP4B1 | ADRA1A 2923/4885TYMS 466/4885MAPKAPK2 2976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.