Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17908021 | 1.00 | PLA2G4B (0.61) | PLA2G4BMAPTLMNAPOLBNPSR1 | |
| SCHEMBL17908101 | 1.00 | PLA2G4B (0.61) | PLA2G4BMAPTLMNAPOLBNPSR1 | |
| SCHEMBL14789253 | 0.95 | PLA2G4B (0.57) | PLA2G4BMAPTLMNAPOLBNPSR1 | |
| Biphenyl SCHEMBL9148056 | 0.92 | PLA2G4B (0.55) | PLA2G4BMAPTLMNAPOLBNPSR1 | |
| SCHEMBL14714485 | 0.92 | PLA2G4B (0.55) | PLA2G4BMAPTLMNAPOLBNPSR1 | |
| SCHEMBL9741323 | 0.91 | PLA2G4B (0.71) | PLA2G4BMAPTLMNAPOLBNPSR1 | |
| SCHEMBL14901508 | 0.87 | LMNA (0.61) | MAPTLMNAPOLBNPSR1MAPK1 | |
| SCHEMBL2384639 | 0.85 | ABCB1 (0.66) | MAPTLMNAPOLBNPSR1MAPK1 | |
| SCHEMBL27896962 | 0.85 | PLA2G4B (0.48) | PLA2G4BMAPTLMNAPOLBNPSR1 | |
| SCHEMBL6228324 | 0.84 | AR (0.61) | MAPTLMNAPOLBNPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936488-B | Novel compounds for the treatment of parasitic infections | 葛兰素史克知识产权开发有限公司 | 2023-06-27 | — | — | CN | disclosed |
| US-11252960-B2 | Antibacterial composition including benzoic acid ester and methods of inhibiting bacterial growth utilizing the same | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2022-02-22 | — | — | US | disclosed |
| US-11224221-B2 | — | — | 2022-01-18 | — | — | US | disclosed |
| CN-111936488-A | Novel compounds for the treatment of parasitic infections | 葛兰素史克知识产权开发有限公司 | 2020-11-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11252960-B2 | Antibacterial composition including benzoic acid ester and methods of inhibiting bacterial growth utilizing the same | DBI, BCAT1, TBCA | PLA2G4B 3660/4885MAPT 4055/4885LMNA 2808/4885 |
| US-11224221-B2 | — | TBCA, SPOUT1, BPGM | PLA2G4B 3484/4885MAPT 4323/4885LMNA 2701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.