SCHEMBL24200042

SCHEMBL24200042

CCC1CCCC(C)N1Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.47
ALDH1A1 P00352 2/20 0.45
GLA P06280 1/20 0.45
HPGD P15428 1/20 0.45
SLC18A2 Q05940 1/20 0.45
POLB P06746 1/20 0.44
ACHE P22303 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17055247 0.86 LTA4H (0.54) LTA4HALDH1A1GLAHPGDSLC18A2
SCHEMBL18557 0.86 LTA4H (0.54) LTA4HALDH1A1GLAHPGDSLC18A2
SCHEMBL10285471 0.82 ALDH1A1 (0.44) LTA4HALDH1A1GLAHPGDSLC18A2
SCHEMBL10077401 0.79 ACHE (0.55) LTA4HALDH1A1GLAHPGDACHE
SCHEMBL11144165 0.79 ACHE (0.55) LTA4HALDH1A1GLAHPGDACHE
SCHEMBL14146467 0.76 KMT2A (0.45) ALDH1A1HPGD
SCHEMBL20330536 0.75 ACHE (0.45) ALDH1A1GLAHPGDACHE
SCHEMBL11452771 0.75 ACHE (0.45) LTA4HACHE
SCHEMBL23043539 0.75 ACHE (0.45) LTA4HALDH1A1GLAHPGDACHE
SCHEMBL27043869 0.75 BRD4 (0.43) ALDH1A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3939954-A1 METHOD FOR INTRODUCING DEUTERATED LOWER ALKYL INTO AMINE MOIETY OF COMPOUND CONTAINING SECONDARY AMINE Otsuka Pharmaceutical Co., Ltd. (JP) 2022-01-19 EP disclosed