Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | FNTA | P49354 | 1/20 | 0.53 |
| ▸ | FNTB | P49356 | 1/20 | 0.53 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25414776 | 0.93 | MEN1 (0.51) | NPSR1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL12018089 | 0.92 | KMT2A (0.56) | NPSR1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL22418871 | 0.91 | SIGMAR1 (0.52) | NPSR1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL16611411 | 0.90 | MEN1 (0.69) | NPSR1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL9819725 | 0.89 | ALDH1A1 (0.64) | SMN1; SMN2CYP2C19PKMALDH1A1KDM4E | |
| SCHEMBL25417483 | 0.89 | ALDH1A1 (0.62) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5109854 | 0.88 | MEN1 (0.71) | NPSR1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL15688093 | 0.88 | TMEM97 (0.60) | NPSR1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL4595454 | 0.88 | KMT2A (0.57) | NPSR1KMT2AMEN1SMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL29864758 | 0.87 | MEN1 (0.69) | NPSR1KMT2AMEN1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630487-B2 | Method for introducing deuterated lower alkyl into amine moiety of compound containing secondary amine | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2026-05-19 | — | — | US | disclosed |
| EP-3939954-B1 | METHOD FOR INTRODUCING DEUTERATED LOWER ALKYL INTO AMINE MOIETY OF COMPOUND CONTAINING SECONDARY AMINE | OTSUKA PHARMA CO LTD (JP) | 2025-07-23 | — | — | EP | disclosed |
| US-20220127206-A1 | METHOD FOR INTRODUCING DEUTERATED LOWER ALKYL INTO AMINE MOIETY OF COMPOUND CONTAINING SECONDARY AMINE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-04-28 | — | — | US | disclosed |
| EP-3939954-A1 | METHOD FOR INTRODUCING DEUTERATED LOWER ALKYL INTO AMINE MOIETY OF COMPOUND CONTAINING SECONDARY AMINE | Otsuka Pharmaceutical Co., Ltd. (JP) | 2022-01-19 | — | — | EP | disclosed |
| EP-3939954-A1 | METHOD FOR INTRODUCING DEUTERATED LOWER ALKYL INTO AMINE MOIETY OF COMPOUND CONTAINING SECONDARY AMINE | Otsuka Pharmaceutical Co., Ltd. (JP) | 2022-01-19 | — | — | EP | disclosed |
| CN-113518771-A | Method for introducing deuterated lower alkyl into amine part of compound containing secondary amine | 大塚制药株式会社 | 2021-10-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127206-A1 | METHOD FOR INTRODUCING DEUTERATED LOWER ALKYL INTO AMINE MOIETY OF COMPOUND CONTAINING SECONDARY AMINE | MGMT, FANCD2, ADAR | NPSR1 3935/4885KMT2A 60/4885MEN1 562/4885 |
| US-12630487-B2 | Method for introducing deuterated lower alkyl into amine moiety of compound containing secondary amine | AZI2, ALKBH2, MGMT | NPSR1 3789/4885KMT2A 64/4885MEN1 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.