Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 4/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | F11 | P03951 | 2/20 | 0.39 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21455128 | 0.90 | CFD (0.50) | CFDPLAUF11TPSB2PLG | |
| SCHEMBL21455691 | 0.78 | TBXAS1 (0.42) | TBXAS1CYP4F2CYP4A11PKMMEN1 | |
| SCHEMBL21455759 | 0.73 | L3MBTL1 (0.40) | CFDTBXAS1DPP4PKMMEN1 | |
| SCHEMBL23617310 | 0.73 | L3MBTL1 (0.40) | CFDTBXAS1DPP4PKMMEN1 | |
| SCHEMBL21455427 | 0.73 | TBXAS1 (0.42) | CFDTBXAS1CYP4F2CYP4A11PKM | |
| SCHEMBL28736136 | 0.72 | CFD (0.73) | CFDPLAUF11TPSB2PLG | |
| SCHEMBL29592574 | 0.72 | CFD (0.73) | CFDPLAUF11TPSB2PLG | |
| SCHEMBL21455544 | 0.71 | TBXAS1 (0.37) | TBXAS1CYP4F2CYP4A11PKMMEN1 | |
| SCHEMBL23229004 | 0.70 | TBXAS1 (0.47) | TBXAS1CYP4F2CYP4A11PKM | |
| SCHEMBL23241478 | 0.70 | TBXAS1 (0.47) | TBXAS1CYP4F2CYP4A11PKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939658-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |