Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CFD | P00746 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23617310 | 0.90 | L3MBTL1 (0.40) | L3MBTL1CFDTBXAS1HTTNPSR1 | |
| SCHEMBL24199940 | 0.79 | L3MBTL1 (0.36) | L3MBTL1CFDTBXAS1HTTNPSR1 | |
| SCHEMBL21455427 | 0.79 | TBXAS1 (0.42) | L3MBTL1CFDTBXAS1HTTPKM | |
| SCHEMBL24200224 | 0.75 | TBXAS1 (0.35) | L3MBTL1CFDTBXAS1HTTNPSR1 | |
| SCHEMBL24200084 | 0.73 | CFD (0.44) | CFDTBXAS1PKMMEN1KMT2A | |
| SCHEMBL21455691 | 0.73 | TBXAS1 (0.42) | L3MBTL1TBXAS1PKMMEN1KMT2A | |
| SCHEMBL21455539 | 0.71 | TBXAS1 (0.36) | L3MBTL1TBXAS1PKMHPGDALDH1A1 | |
| SCHEMBL21455716 | 0.71 | TBXAS1 (0.37) | L3MBTL1TBXAS1HTTNPSR1PKM | |
| SCHEMBL909198 | 0.71 | TBXAS1 (0.48) | L3MBTL1TBXAS1PKMMEN1KMT2A | |
| SCHEMBL21455544 | 0.70 | TBXAS1 (0.37) | L3MBTL1TBXAS1HTTNPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939658-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |
| WO-2019195720-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2019-10-10 | — | — | WO | disclosed |