Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21455708 | 0.79 | TBXAS1 (0.41) | TBXAS1L3MBTL1TSHRHPGDALDH1A1 | |
| SCHEMBL21455759 | 0.75 | L3MBTL1 (0.40) | TBXAS1CFDL3MBTL1TSHRHPGD | |
| SCHEMBL23617310 | 0.75 | L3MBTL1 (0.40) | TBXAS1CFDL3MBTL1TSHRHPGD | |
| SCHEMBL21455186 | 0.73 | TBXAS1 (0.37) | TBXAS1L3MBTL1TSHRHPGDALDH1A1 | |
| SCHEMBL23241478 | 0.71 | TBXAS1 (0.47) | TBXAS1L3MBTL1TSHRHPGDALDH1A1 | |
| SCHEMBL23425588 | 0.71 | TBXAS1 (0.47) | TBXAS1L3MBTL1TSHRHPGDALDH1A1 | |
| SCHEMBL24200116 | 0.71 | KAT6A (0.33) | MRGPRX4 | |
| SCHEMBL21455709 | 0.70 | TBXAS1 (0.46) | TBXAS1L3MBTL1TSHRHPGDALDH1A1 | |
| SCHEMBL24199940 | 0.70 | L3MBTL1 (0.36) | TBXAS1CFDL3MBTL1TSHRHPGD | |
| SCHEMBL23229004 | 0.69 | TBXAS1 (0.47) | TBXAS1L3MBTL1ALDH1A1HSD17B10PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939658-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |