Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | BMP1 | P13497 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28647737 | 0.81 | MAPT (0.44) | MAPTLTB4R2L3MBTL1CCR2BMP1 | |
| SCHEMBL22436191 | 0.81 | CNR1 (0.57) | MAPTL3MBTL1CACNA1BCACNA1CTAS2R14 | |
| SCHEMBL28645985 | 0.80 | TAS2R14 (0.47) | MAPTLTB4R2L3MBTL1HTR6BMP1 | |
| SCHEMBL1498496 | 0.72 | HTR6 (0.44) | HTR6CACNA1BCA1CA2RORC | |
| SCHEMBL29953233 | 0.69 | L3MBTL1 (0.57) | MAPTL3MBTL1TAS2R14CNR1CNR2 | |
| SCHEMBL8360843 | 0.69 | CNR1 (0.49) | MAPTL3MBTL1BMP1TAS2R14RORC | |
| SCHEMBL13932919 | 0.68 | CACNA1B (0.50) | CACNA1BALDH1A1 | |
| SCHEMBL23012243 | 0.67 | TAS2R14 (0.65) | MAPTTAS2R14CNR1CNR2 | |
| SCHEMBL4928804 | 0.67 | MAPK1 (0.43) | MAPTALDH1A1GAA | |
| SCHEMBL23012376 | 0.67 | TAS2R14 (0.61) | MAPTBMP1TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939979-A1 | JAK KINASE INHIBITOR, PREPARATION METHOD FOR SAME, AND APPLICATIONS THEREOF IN FIELD OF MEDICINE | Shanghai Synergy Pharmaceutical Sciences Co., Ltd (CN) | 2022-01-19 | — | — | EP | disclosed |