SCHEMBL24201

SCHEMBL24201

O=C(Cl)c1ccccc1C(F)(F)F

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.60
GAA P10253 1/20 0.60
ALDH1A1 P00352 1/20 0.54
ALOX15 P16050 1/20 0.54
CTNNB1 P35222 3/20 0.49
WNT3A P56704 3/20 0.49
CNR2 P34972 2/20 0.47
PTGS1 P23219 1/20 0.45
KCNK3 O14649 1/20 0.45
KCNK9 Q9NPC2 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NFKB1 P19838 1/20 0.44
PPIA P62937 1/20 0.43
TAS2R14 Q9NYV8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoyl Chloride SCHEMBL8103514 0.91 LMNA (0.51) LMNAGAAALDH1A1ALOX15CTNNB1
Toluene SCHEMBL19876750 0.89 LMNA (0.50) LMNAGAAALDH1A1ALOX15CTNNB1
SCHEMBL7722324 0.89 GAA (0.50) LMNAGAAALDH1A1ALOX15CTNNB1
SCHEMBL10887048 0.85 ALDH1A1 (0.52) LMNAGAAALDH1A1ALOX15CTNNB1
SCHEMBL15924001 0.85 ALDH1A1 (0.52) LMNAGAAALDH1A1ALOX15CTNNB1
SCHEMBL10895833 0.85 ALDH1A1 (0.52) LMNAGAAALDH1A1ALOX15CTNNB1
SCHEMBL8675691 0.85 ALDH1A1 (0.49) LMNAGAAALDH1A1ALOX15CTNNB1
SCHEMBL6584239 0.84 LMNA (0.49) LMNAGAAALDH1A1ALOX15CTNNB1
SCHEMBL4111692 0.83 ALDH1A1 (0.50) LMNAGAAALDH1A1ALOX15CTNNB1
SCHEMBL27926996 0.83 ALDH1A1 (0.50) LMNAGAAALDH1A1ALOX15CTNNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2672 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122071504-A Oxime-decorated glycosyl thioether, and preparation method and application thereof 四川大学华西医院 2026-05-22 CN claimed
CN-120081783-A Fluopicola strain Process for the preparation of amides 天津均凯农业科技有限公司 2025-06-03 CN claimed
CN-120082181-A PBAT/bamboo powder biodegradable composite master batch, preparation method thereof and composite film 国际竹藤中心 2025-06-03 CN claimed
CN-120020114-A Preparation method of N-alkenyl amide compound 中国石油化工股份有限公司 2025-05-20 CN claimed
CN-120020115-A Process for the preparation of N- (alkyl-2-hydroxy) alkylamides and N-alkenylamides 中国石油化工股份有限公司 2025-05-20 CN claimed
CN-119771181-A Preparation method and process of oxidation-resistant reverse osmosis membrane 上海陕煤高新技术研究院有限公司 2025-04-08 CN claimed
CN-119777031-A Polysaccharide-based thermoplastic composite fiber and preparation method thereof 中国科学院化学研究所 2025-04-08 CN claimed
CN-119751343-A Fluopicola strain Process for the preparation of amides 天津均凯农业科技有限公司 2025-04-04 CN claimed
CN-119592003-A Low-dielectric high-flame-retardance cable material and preparation method and application thereof 宁波聚泰新材料科技有限公司 2025-03-11 CN claimed
CN-115819280-B T.bufalin Process for the preparation of esters 天津均凯农业科技有限公司 2025-02-18 CN claimed
EP-1569925-A1 2-SUBSTITUTED QUINAZOLIN-4-YLAMINE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS NEUROGEN CORPORATION (US) 2005-09-07 EP claimed
CN-1216028-C Preparation method of 3,5-di (trifluoromethyl) benzoyl chloride and new 3,5-di(triahlo) benzoylate A and 3,5-dimethyl benzoylate A BAYER AG (DE) 2005-08-24 CN claimed
WO-2004055003-A1 2-SUBSTITUTED QUINAZOLIN-4-YLAMINE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS NEUROGEN CORPORATION (US) 2004-07-01 WO claimed
CN-1308050-A Preparation method of 3,5-di (trifluoromethyl) benzoyl chloride and new 3,5-di(triahlo) benzoylate A and 3,5-dimethyl benzoylate A BAYER AG (DE) 2001-08-15 CN claimed
WO-1993014055-A1 PREPARATION OF 2,5-DICHLOROBENZOPHENONES MAXDEM INCORPORATED (US) 1993-07-22 WO claimed
US-5210313-A Friedel crafts aryloylation of 1,4-dichlorobenzene and Lewis acids MAXDEM INCORPORATED (US) 1993-05-11 US claimed
US-4581179-A Process for the preparation of trifluoromethylbenzoyl chlorides and bromides from trifluoromethylbenzoyl fluorides OCCIDENTAL CHEMICAL CORPORATION (US) 1986-04-08 US claimed
US-4500471-A REACTING TRICHLORO-OR TRIBROMOMETHYLBENZOYL HALIDES WITH HYDROGEN FLORIDE OCCIDENTAL CHEMICAL CORPORATION (US) 1985-02-19 US claimed
EP-0038223-B1 PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYLBENZOYL HALIDES OCCIDENTAL CHEMICAL CORPORATION (US) 1984-08-08 EP claimed
EP-0038223-A1 Process for the preparation of trifluoromethylbenzoyl halides OCCIDENTAL CHEMICAL CORPORATION (US) 1981-10-21 EP claimed