Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.43 |
| ▸ | WNT3A | P56704 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24201 | 0.91 | LMNA (0.60) | LMNAGAAKCNK3KCNK9ALDH1A1 | |
| Benzoyl Chloride SCHEMBL8176963 | 0.87 | LMNA (0.44) | LMNAGAAKCNK3KCNK9ALDH1A1 | |
| Toluene SCHEMBL19876750 | 0.84 | LMNA (0.50) | LMNAGAAKCNK3KCNK9ALDH1A1 | |
| SCHEMBL7722324 | 0.81 | GAA (0.50) | LMNAGAAKCNK3KCNK9ALDH1A1 | |
| SCHEMBL9225679 | 0.80 | KCNK3 (0.49) | LMNAGAAKCNK3KCNK9POLB | |
| SCHEMBL3717986 | 0.79 | GAA (0.56) | LMNAGAAKCNK3KCNK9ALDH1A1 | |
| SCHEMBL31369140 | 0.79 | GAA (0.56) | LMNAGAAKCNK3KCNK9ALDH1A1 | |
| SCHEMBL27524184 | 0.78 | LMNA (0.55) | LMNAGAAKCNK3KCNK9CTNNB1 | |
| SCHEMBL10895833 | 0.77 | ALDH1A1 (0.52) | LMNAGAAALDH1A1ALOX15CTNNB1 | |
| SCHEMBL15924001 | 0.77 | ALDH1A1 (0.52) | LMNAGAAALDH1A1ALOX15CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973936-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998057173-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED PHENYLALANINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-12-17 | — | — | WO | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| WO-1998008839-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED THIOPHENE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |
| WO-1998008813-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED PYRROLIDINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |