Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.46 |
| ▸ | FPR2 | P25090 | 6/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24201119 | 0.77 | FPR2 (0.48) | CSNK2A2CSNK2A1FPR2ESR1SMN1; SMN2 | |
| SCHEMBL27505442 | 0.76 | FPR2 (0.40) | CSNK2A2CSNK2A1FPR2ESR1SMN1; SMN2 | |
| SCHEMBL4288735 | 0.76 | FPR2 (0.40) | CSNK2A2CSNK2A1FPR2ESR1SMN1; SMN2 | |
| SCHEMBL369240 | 0.76 | ALPL (0.54) | ESR1SMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL938206 | 0.76 | ARG1 (0.53) | CSNK2A2CSNK2A1FPR2ESR1SMN1; SMN2 | |
| SCHEMBL3587986 | 0.74 | FPR2 (0.49) | CSNK2A2CSNK2A1FPR2ESR1SMN1; SMN2 | |
| SCHEMBL28938190 | 0.74 | ALPL (0.53) | ESR1SMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL17669581 | 0.74 | FPR2 (0.52) | CSNK2A2CSNK2A1FPR2ESR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28835895 | 0.74 | ALPL (0.55) | ESR1SMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL371254 | 0.73 | ALPG (0.56) | FPR2ESR1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2706057-B1 | Bis(imidazolyl)compounds and radionuclide complexes | MOLECULAR INSIGHT PHARM INC (US) | 2016-04-20 | — | — | EP | disclosed |
| EP-2706057-A1 | Bis(imidazolyl)compounds and radionuclide complexes | Molecular Insight Pharmaceuticals, Inc. (US) | 2014-03-12 | — | — | EP | disclosed |