Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.53 |
| ▸ | DRD4 | P21917 | 5/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14200380 | 0.86 | NOTUM (0.47) | DRD2DRD4NOTUMALDH1A1NPC1 | |
| SCHEMBL29571640 | 0.81 | DRD2 (0.47) | DRD2DRD4NOTUMALDH1A1NPC1 | |
| SCHEMBL3061256 | 0.81 | DRD2 (0.47) | DRD2DRD4NOTUMALDH1A1NPC1 | |
| SCHEMBL30681381 | 0.81 | DRD2 (0.47) | DRD2DRD4NOTUMALDH1A1NPC1 | |
| SCHEMBL1760601 | 0.81 | DRD2 (0.47) | DRD2DRD4NOTUMALDH1A1NPC1 | |
| SCHEMBL30390423 | 0.81 | DRD2 (0.47) | DRD2DRD4NOTUMALDH1A1NPC1 | |
| SCHEMBL30681441 | 0.79 | DRD2 (0.53) | DRD2DRD4NOTUMALDH1A1NPC1 | |
| SCHEMBL7554164 | 0.79 | DRD2 (0.53) | DRD2DRD4NOTUMALDH1A1NPC1 | |
| SCHEMBL4289075 | 0.79 | DRD2 (0.53) | DRD2DRD4NOTUMALDH1A1NPC1 | |
| SCHEMBL14200379 | 0.76 | MTNR1A (0.50) | PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939981-A1 | FUSED THIAZOLOPYRIMIDINE DERIVATIVES AS MNKS INHIBITORS | LifeArc (GB) | 2022-01-19 | — | — | EP | disclosed |