Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27665631 | 0.82 | CYP2C9 (0.40) | ALDH1A1TDP1KMT2A | |
| SCHEMBL7607986 | 0.71 | CRHR1 (0.36) | ALDH1A1TDP1TAAR1CRHR1KMT2A | |
| SCHEMBL19231144 | 0.71 | ALDH1A1 (0.41) | ALDH1A1TDP1TAAR1KMT2A | |
| SCHEMBL8284306 | 0.71 | ALDH1A1 (0.41) | ALDH1A1TDP1TAAR1KMT2A | |
| SCHEMBL13091241 | 0.70 | ALDH1A1 (0.38) | ALDH1A1TDP1TAAR1KMT2A | |
| SCHEMBL27665322 | 0.70 | TAS1R3 (0.39) | ALDH1A1TDP1KMT2A | |
| Hydrochloric Acid SCHEMBL4927027 | 0.69 | ALDH1A1 (0.40) | ALDH1A1TDP1TAAR1KMT2A | |
| Hydrochloric Acid SCHEMBL23527453 | 0.69 | ALDH1A1 (0.40) | ALDH1A1TDP1TAAR1KMT2A | |
| SCHEMBL27665829 | 0.69 | SLC1A3 (0.41) | ALDH1A1 | |
| SCHEMBL27391010 | 0.69 | TSHR (0.42) | ALDH1A1TDP1TAAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939981-A1 | FUSED THIAZOLOPYRIMIDINE DERIVATIVES AS MNKS INHIBITORS | LifeArc (GB) | 2022-01-19 | — | — | EP | disclosed |