Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5492047 | 0.79 | KMT2A (0.34) | KMT2APOLBNR3C1NR3C2LMNA | |
| SCHEMBL24201976 | 0.71 | ALDH1A1 (0.34) | CRHR1KMT2AALDH1A1TDP1TAAR1 | |
| SCHEMBL27391010 | 0.70 | TSHR (0.42) | KMT2APOLBNR3C1NR3C2LMNA | |
| SCHEMBL19231144 | 0.68 | ALDH1A1 (0.41) | KMT2APOLBNR3C1NR3C2LMNA | |
| SCHEMBL8133440 | 0.68 | HTT (0.40) | KMT2APOLBLMNAALDH1A1TDP1 | |
| SCHEMBL1005595 | 0.68 | TDP1 (0.37) | CRHR1KMT2APOLBNR3C1NR3C2 | |
| SCHEMBL9094407 | 0.68 | HTT (0.40) | KMT2APOLBLMNAALDH1A1TDP1 | |
| SCHEMBL8284306 | 0.68 | ALDH1A1 (0.41) | KMT2APOLBNR3C1NR3C2LMNA | |
| SCHEMBL5483548 | 0.68 | CASR (0.38) | NR3C1NR3C2LMNAALDH1A1TDP1 | |
| SCHEMBL27665829 | 0.67 | SLC1A3 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |