Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DBH | P09172 | 4/20 | 0.32 |
| ▸ | LPO | P22079 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24205048 | 0.77 | NPC1 (0.39) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL11565383 | 0.73 | — | — | |
| SCHEMBL24205457 | 0.64 | LMNA (0.32) | ALDH1A1SMN1; SMN2KDM4ELPOLMNA | |
| SCHEMBL24205141 | 0.64 | CYP1A2 (0.48) | ALDH1A1KMT2AMEN1MAPTPTGS1 | |
| SCHEMBL24205037 | 0.63 | — | — | |
| SCHEMBL9248493 | 0.63 | LPO (0.52) | KDM4EKMT2AMEN1MAPTLPO | |
| SCHEMBL24205178 | 0.61 | MAPK1 (0.45) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL27938781 | 0.61 | — | — | |
| SCHEMBL9523550 | 0.59 | — | — | |
| SCHEMBL24709729 | 0.59 | DUT (0.41) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022012798-A1 | OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2022-01-20 | — | — | WO | disclosed |