SCHEMBL2420565

SCHEMBL2420565

CCCCOC(=O)C(Br)(Br)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.53
TDP1 Q9NUW8 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
CYP3A4 P08684 5/20 0.48
ALDH1A1 P00352 3/20 0.48
MAPK1 P28482 2/20 0.48
TP53 P04637 1/20 0.47
CYP2D6 P10635 3/20 0.47
LMNA P02545 3/20 0.47
SCN1A P35498 3/20 0.47
SCN2A Q99250 3/20 0.47
SCN3A Q9NY46 3/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 2/20 0.47
NFKB1 P19838 1/20 0.47
MTOR P42345 1/20 0.47
RAB9A P51151 1/20 0.47
SIGMAR1 Q99720 1/20 0.47
CHRM2 P08172 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2417813 0.90 LMNA (0.53) TSHRCYP3A4ALDH1A1CYP2D6LMNA
SCHEMBL2418304 0.87 TSHR (0.53) TSHRTDP1L3MBTL1CYP3A4ALDH1A1
SCHEMBL8168380 0.85 KCNN4 (0.55) TSHRTDP1L3MBTL1CYP3A4ALDH1A1
SCHEMBL28558105 0.85 TSHR (0.54) TSHRTDP1L3MBTL1CYP3A4ALDH1A1
SCHEMBL10029779 0.83 CHRM2 (0.66) TSHRTDP1L3MBTL1CYP3A4ALDH1A1
SCHEMBL14258113 0.83 TSHR (0.53) TSHRTDP1L3MBTL1CYP3A4ALDH1A1
SCHEMBL5161453 0.83 MEN1 (0.64) TSHRTDP1L3MBTL1CYP3A4ALDH1A1
SCHEMBL16732083 0.83 TSHR (0.53) TSHRTDP1L3MBTL1CYP3A4ALDH1A1
SCHEMBL27340330 0.83 TSHR (0.53) TSHRTDP1L3MBTL1CYP3A4ALDH1A1
SCHEMBL2420371 0.82 PIN1 (0.54) TSHRALDH1A1RAB9ACHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8278404-B2 Process for producing copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-02 US disclosed
US-20110224390-A1 PROCESS FOR PRODUCING COPOLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-09-15 US disclosed
US-7262258-B2 Process for producing copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-08-28 US disclosed
US-20070088139-A1 PROCESS FOR PRODUCING COPOLYMER SUMITOMO CHEMICAL COMPANY, LIMITED 2007-04-19 US disclosed
US-20050014914-A1 Process for producing copolymer SUMITOMO CHEMICAL COMPANY, LIMITED 2005-01-20 US disclosed