SCHEMBL24206

SCHEMBL24206

[c]1ccc2c(c1)-c1ccccc1C2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.46
MAPT P10636 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
HPGD P15428 2/20 0.44
KDM4E B2RXH2 2/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
ALDH1A1 P00352 2/20 0.44
LMNA P02545 1/20 0.44
SRD5A2 P31213 1/20 0.39
BCHE P06276 1/20 0.39
CES1 P23141 1/20 0.39
METAP2 P50579 1/20 0.37
PLK4 O00444 1/20 0.37
DAPK3 O43293 1/20 0.37
PIM1 P11309 1/20 0.37
PDGFRA P16234 1/20 0.37
LTK P29376 1/20 0.37
MAP2K2 P36507 1/20 0.37
FLT3 P36888 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68422 0.89 MAOA (0.33) MAOA
SCHEMBL4312831 0.87 CES1 (0.46) MAOAHPGDKDM4ENPC1RAB9A
SCHEMBL24657 0.87 MAOA (0.46) MAOAMAPTSMN1; SMN2HPGDKDM4E
SCHEMBL2678990 0.84
SCHEMBL27537566 0.84 MAOA (0.67) MAOAMAPTSMN1; SMN2KDM4ENPC1
Fluorene SCHEMBL27849096 0.81 MAOA (0.65) MAOAMAPTSMN1; SMN2HPGDKDM4E
SCHEMBL1789802 0.79 CYP1A2 (0.40) MAOAMAPTSMN1; SMN2HPGDKDM4E
SCHEMBL6537887 0.78
Fluorene SCHEMBL28014522 0.78 MAOA (0.62) MAOAMAPTSMN1; SMN2HPGDKDM4E
Fluorene SCHEMBL8180 0.78 MAOA (0.68) MAOAMAPTSMN1; SMN2HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2462 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112079786-B Compound, organic electronic light-emitting device containing compound and application of compound 北京鼎材科技有限公司 2024-05-21 CN claimed
WO-2024099269-A1 ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, USE THEREOF 华东师范大学 2024-05-16 WO claimed
CN-118026880-A Aryl amide compound, pharmaceutical composition containing same and application thereof 华东师范大学 2024-05-14 CN claimed
CN-112094169-B Organic electroluminescent material and application thereof 北京鼎材科技有限公司 2024-03-26 CN claimed
CN-112441977-B Compound, application thereof and organic electroluminescent device comprising compound 北京鼎材科技有限公司 2024-03-19 CN claimed
CN-111341920-B Organic electroluminescent device 固安鼎材科技有限公司 2024-01-30 CN claimed
CN-112018248-B Display device and preparation method thereof 固安鼎材科技有限公司 2023-12-29 CN claimed
WO-2023247416-A1 TETRAARYLBENZIDINE TYPE COMPOUNDS AND THEIR USE IN ORGANIC ELECTRONICS DOTTIKON ES HOLDING AG (CH) 2023-12-28 WO claimed
CN-116854599-A Tetraphenyl ethylene derivative and organic electroluminescent device comprising same 广东省大湾区华南理工大学聚集诱导发光高等研究院 2023-10-10 CN claimed
US-20230225209-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD (CN) 2023-07-13 US claimed
EP-0836596-A1 HYDRAZINE DERIVATIVES UNIROYAL CHEMICAL COMPANY, Inc. (US) 1998-04-22 EP claimed
CN-1144526-A Thiazolidines and oxazolidines substituted by pyridine ring and their use a hypoglycemic agents NISSAN CHEMICAL IND LTD (JP) 1997-03-05 CN claimed
WO-1997002257-A1 HYDRAZINE DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. (US) 1997-01-23 WO claimed
EP-0751944-A1 THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1997-01-08 EP claimed
US-5567723-A Miticidal hydrazine compounds and their intermediates UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-10-22 US claimed
WO-1996002517-A1 SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS DR. KARL THOMAE GMBH (DE) 1996-02-01 WO claimed
WO-1995026347-A1 THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1995-10-05 WO claimed
EP-0626947-A1 HYDROISOINDOLINES AND HYDROISOQUINOLINES AS PSYCHOTROPIC DRUGS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1994-12-07 EP claimed
US-5254546-A Hypotensive agent E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-10-19 US claimed
WO-1993016047-A1 HYDROISOINDOLINES AND HYDROISOQUINOLINES AS PSYCHOTROPIC DRUGS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-08-19 WO claimed