SCHEMBL24657

SCHEMBL24657

[c]1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.46
KDM4E B2RXH2 2/20 0.44
NPC1 O15118 2/20 0.44
MAPT P10636 2/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
ALDH1A1 P00352 2/20 0.44
LMNA P02545 1/20 0.44
HPGD P15428 1/20 0.44
SRD5A2 P31213 1/20 0.39
BCHE P06276 1/20 0.39
CES1 P23141 1/20 0.39
PLK4 O00444 1/20 0.37
DAPK3 O43293 1/20 0.37
PIM1 P11309 1/20 0.37
PDGFRA P16234 1/20 0.37
LTK P29376 1/20 0.37
MAP2K2 P36507 1/20 0.37
FLT3 P36888 1/20 0.37
MAPK8 P45983 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL71211 0.89
SCHEMBL24206 0.87 MAOA (0.46) MAOAKDM4ENPC1MAPTRAB9A
SCHEMBL2678990 0.84
SCHEMBL476341 0.83 CES1 (0.46) MAOAKDM4ENPC1RAB9AALDH1A1
Fluorene SCHEMBL27849096 0.81 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A
SCHEMBL2238415 0.80 NPC1 (0.32) KDM4ENPC1MAPTRAB9ASMN1; SMN2
SCHEMBL1789802 0.79 CYP1A2 (0.40) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL28014522 0.78 MAOA (0.62) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL28160584 0.78 MAOA (0.62) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL8180 0.78 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4811 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063384-A Aromatic ring substituted pyrazole derivative and application thereof 四川农业大学 2024-05-24 CN claimed
CN-112079786-B Compound, organic electronic light-emitting device containing compound and application of compound 北京鼎材科技有限公司 2024-05-21 CN claimed
WO-2024099269-A1 ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, USE THEREOF 华东师范大学 2024-05-16 WO claimed
CN-118026880-A Aryl amide compound, pharmaceutical composition containing same and application thereof 华东师范大学 2024-05-14 CN claimed
CN-118044355-A Compounds for electronic devices 默克专利有限公司 2024-05-14 CN claimed
US-20240107870-A1 POLYMER, COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC EL DISPLAY DEVICE, ORGANIC EL LIGHTING, AND MANUFACTURING METHOD FOR ORGANIC ELECTROLUMINESCENT ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2024-03-28 US claimed
US-11943997-B2 Polymer, composition for organic electroluminescent element, organic electroluminescent element, organic EL display device, organic EL lighting, and manufacturing method for organic electroluminescent element MITSUBISHI CHEMICAL CORPORATION (JP) 2024-03-26 US claimed
CN-117757066-A Polymer, composition for organic EL element, and method for producing same 三菱化学株式会社 2024-03-26 CN claimed
CN-112094169-B Organic electroluminescent material and application thereof 北京鼎材科技有限公司 2024-03-26 CN claimed
CN-117757067-A Polymer, composition for organic EL element, and method for producing same 三菱化学株式会社 2024-03-26 CN claimed
EP-0658539-A1 Excitatory amino acid receptor antagonists ELI LILLY AND COMPANY (US) 1995-06-21 EP claimed
WO-1995009847-A1 PYRIMIDINEAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF CIBA-GEIGY AG (CH) 1995-04-13 WO claimed
US-5405864-A Chemotherapeutic maleimides SYNTEX (U.S.A.) INC. (US) 1995-04-11 US claimed
US-5399707-A Selective precipitation of α-aryl carboxylic acid salts HOECHST CELANESE CORPORATION (US) 1995-03-21 US claimed
US-5380867-A Selective precipitation of α-aryl carboxylic acid salts HOECHST CELANESE CORPORATION (US) 1995-01-10 US claimed
US-5332834-A Nonsteroid antiinflammatory agents HOECHST CELANESE CORPORATION (US) 1994-07-26 US claimed
WO-1994012451-A1 SELECTIVE PRECIPITATION OF α-ARYL CARBOXYLIC ACID SALTS HOECHST CELANESE CORPORATION (US) 1994-06-09 WO claimed
EP-0190946-B1 NOVEL CYCLIC HEXAPEPTIDE LHRH ANTAGONISTS MERCK & CO. INC. (US) 1993-01-20 EP claimed
EP-0194764-B1 PESTICIDAL COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1989-07-12 EP claimed
EP-0194764-A1 Pesticidal compounds THE WELLCOME FOUNDATION LIMITED (GB) 1986-09-17 EP claimed