Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15160739 | 0.83 | TAAR1 (0.45) | TAAR1IDO1AOC3SLC6A2SLC6A3 | |
| SCHEMBL139640 | 0.82 | GABRA1 (0.52) | TAAR1IDO1AOC3SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL4680288 | 0.82 | CYP2D6 (0.52) | TAAR1IDO1AOC3SLC6A2SLC6A3 | |
| SCHEMBL24967350 | 0.79 | TAAR1 (0.42) | TAAR1IDO1AOC3SLC6A2SLC6A3 | |
| SCHEMBL5680506 | 0.79 | TAAR1 (0.42) | TAAR1IDO1AOC3SLC6A2SLC6A3 | |
| SCHEMBL2563200 | 0.78 | TAAR1 (0.50) | TAAR1IDO1AOC3SLC6A2SLC6A3 | |
| SCHEMBL22204358 | 0.78 | TAAR1 (0.45) | TAAR1IDO1AOC3SLC6A2SLC6A3 | |
| SCHEMBL3238216 | 0.78 | TAAR1 (0.50) | TAAR1IDO1AOC3SLC6A2SLC6A3 | |
| SCHEMBL14478267 | 0.78 | TAAR1 (0.50) | TAAR1IDO1AOC3SLC6A2SLC6A3 | |
| SCHEMBL15082795 | 0.78 | TAAR1 (0.45) | TAAR1IDO1AOC3SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017541-A1 | INHIBITORS OF ARGINASE | Praxis Biotech LLC | 2022-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220017541-A1 | INHIBITORS OF ARGINASE | ARG1, ARG2, ARGLU1 | TAAR1 1533/4885IDO1 167/4885AOC3 238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.