Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24214331 | 0.80 | HDAC3 (0.47) | ALOX5MAPTLMNAALDH1A1NPC1 | |
| SCHEMBL24214288 | 0.78 | BCHE (0.43) | BCHEMAPTLMNAALDH1A1NPC1 | |
| SCHEMBL24214327 | 0.78 | ALDH1A1 (0.50) | ALOX5BCHEMAPTLMNAALDH1A1 | |
| SCHEMBL1981436 | 0.75 | BCHE (0.58) | BCHEMAPTLMNAALDH1A1NPC1 | |
| SCHEMBL5068294 | 0.74 | ALDH1A1 (0.53) | BCHEMAPTLMNAALDH1A1NPC1 | |
| SCHEMBL3255804 | 0.73 | BCHE (0.50) | ALOX5BCHEMAPTLMNAALDH1A1 | |
| SCHEMBL4159541 | 0.73 | HPGD (0.55) | BCHEMAPTLMNAALDH1A1NPC1 | |
| SCHEMBL9099206 | 0.72 | ALDH1A1 (0.54) | ALOX5MAPTLMNAALDH1A1NPC1 | |
| SCHEMBL9099219 | 0.72 | ALDH1A1 (0.54) | ALOX5MAPTLMNAALDH1A1NPC1 | |
| SCHEMBL19385934 | 0.71 | HPGD (0.69) | ALOX5MAPTLMNAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022013564-A1 | PHOTOREDOX PROTEIN MODIFICATION | THE ROSALIND FRANKLIN INSTITUTE (GB) | 2022-01-20 | — | — | WO | disclosed |