Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | RXFP3 | Q9NSD7 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
| ▸ | MAP2 | P11137 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25493087 | 0.76 | GABRA1 (0.39) | IDO1ARAHRCYP1A2HTR2A | |
| SCHEMBL672970 | 0.73 | TRIM24 (0.56) | CYP1A2RXFP3MAPTSMN1; SMN2LMNA | |
| SCHEMBL31375034 | 0.73 | F7 (0.51) | CYP3A4CYP1A2KMO | |
| SCHEMBL25293329 | 0.69 | CHRNB2 (0.36) | CHUK | |
| SCHEMBL27648661 | 0.68 | BRPF1 (0.39) | CYP3A4CYP1A2KMO | |
| SCHEMBL16727213 | 0.68 | CYP1A2 (0.42) | CD44CYP3A4IDO1TSHRAR | |
| SCHEMBL7291123 | 0.68 | CCR8 (0.50) | TP53CYP1A2SMN1; SMN2LMNA | |
| SCHEMBL25024454 | 0.67 | LMNA (0.38) | CD44CYP3A4TSHRMAPK1AR | |
| SCHEMBL30233803 | 0.67 | LMNA (0.38) | CD44CYP3A4TSHRMAPK1AR | |
| SCHEMBL24208558 | 0.67 | HTR2A (0.32) | CYP3A4TSHRMAPK1HTR2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022015957-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2022-01-20 | — | — | WO | disclosed |