Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2417097 | 0.87 | S1PR1 (0.43) | S1PR1LMNAALDH1A1GAAMEN1 | |
| SCHEMBL2421361 | 0.80 | MEN1 (0.42) | S1PR1LMNAALDH1A1GAAMEN1 | |
| SCHEMBL2417802 | 0.80 | GAA (0.42) | S1PR1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL2414362 | 0.79 | GAA (0.41) | S1PR1LMNAALDH1A1GAAMEN1 | |
| SCHEMBL2424612 | 0.74 | GAA (0.41) | S1PR1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL2424610 | 0.74 | L3MBTL1 (0.40) | S1PR1ALDH1A1GAAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7343358 | 0.71 | KMT2A (0.66) | S1PR1LMNAALDH1A1GAAMEN1 | |
| SCHEMBL2417832 | 0.71 | GAA (0.48) | S1PR1LMNAALDH1A1GAAMEN1 | |
| SCHEMBL22946244 | 0.69 | LMNA (0.58) | LMNAALDH1A1GAAPOLBHPGD | |
| SCHEMBL29633534 | 0.69 | LMNA (0.58) | LMNAALDH1A1GAAPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026255-B2 | Substituted piperidines as somatostatin receptor subtype 5 (SSTR5) antagonists | HOFFMAN-LA ROCHE INC. (US) | 2011-09-27 | — | — | US | disclosed |