Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NOS1 | P29475 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13800970 | 0.85 | PRMT6 (0.57) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL13574521 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KDM4EMEN1KMT2AHRH3 | |
| SCHEMBL11196105 | 0.83 | NCF1 (0.83) | NCF1ALDH1A1HTTKDM4EHPGD | |
| SCHEMBL21884103 | 0.80 | HRH3 (0.65) | ALDH1A1KDM4ENOS1MEN1KMT2A | |
| SCHEMBL10235392 | 0.79 | NCF1 (0.71) | NCF1ALDH1A1HTTKDM4EHPGD | |
| SCHEMBL178443 | 0.79 | NCF1 (0.66) | NCF1ALDH1A1HTTKDM4EHPGD | |
| SCHEMBL10190892 | 0.76 | NCF1 (0.67) | NCF1ALDH1A1HTTKDM4EHPGD | |
| SCHEMBL10244180 | 0.76 | NCF1 (0.67) | NCF1ALDH1A1HTTKDM4EHPGD | |
| SCHEMBL1663089 | 0.76 | NCF1 (0.66) | NCF1ALDH1A1HTTKDM4EHPGD | |
| SCHEMBL22711383 | 0.76 | NCF1 (0.71) | NCF1ALDH1A1HTTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024134657-A1 | PYRROLOPYRIDINE AND PYRROLOPYRIDAZINE BASED COMPOUNDS AND USE THEREOF AS PKR INHIBITORS | PROTEKT THERAPEUTICS LTD. (IL) | 2024-06-27 | — | — | WO | disclosed |
| WO-2022026823-A1 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CHAN ZUCKERBERG BIOHUB, INC. (US) | 2022-02-03 | — | — | WO | disclosed |