Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13574521 | 0.98 | ALDH1A1 (0.58) | PRMT6ALDH1A1SMN1; SMN2TDP1KMT2A | |
| SCHEMBL24233058 | 0.85 | NCF1 (0.60) | ALDH1A1SMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL7813992 | 0.81 | SMN1; SMN2 (0.54) | PRMT6ALDH1A1SMN1; SMN2TDP1GAA | |
| SCHEMBL7805242 | 0.80 | SMN1; SMN2 (0.53) | PRMT6ALDH1A1SMN1; SMN2TDP1GAA | |
| SCHEMBL11339852 | 0.79 | PRMT6 (0.78) | PRMT6ALDH1A1SMN1; SMN2TDP1GAA | |
| SCHEMBL11192726 | 0.79 | PRMT6 (0.78) | PRMT6ALDH1A1SMN1; SMN2TDP1GAA | |
| SCHEMBL7813997 | 0.79 | SMN1; SMN2 (0.55) | PRMT6ALDH1A1SMN1; SMN2TDP1GAA | |
| SCHEMBL7805238 | 0.79 | SMN1; SMN2 (0.51) | PRMT6ALDH1A1SMN1; SMN2TDP1GAA | |
| SCHEMBL24093249 | 0.78 | ALDH1A1 (0.61) | PRMT6ALDH1A1SMN1; SMN2TDP1GAA | |
| SCHEMBL12622771 | 0.77 | PRMT6 (0.68) | PRMT6ALDH1A1SMN1; SMN2TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156642-A1 | 5-Membered heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
| US-20090156642-A1 | 5-Membered heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156642-A1 | 5-Membered heterocyclic compound | CEL, PGA5, COG5 | PRMT6 4420/4885ALDH1A1 1497/4885SMN1; SMN2 4327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.