SCHEMBL24235602

SCHEMBL24235602

CC(C)(C)OC(=O)CCC(NC(=O)CNC(=O)CCC(NC(=O)CCC(N)C(=O)NC(CCC(=O)NCC(=O)NC(CCC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)NCC(=O)NC(CCC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)NCC(=O)NC(CCC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ GLO1 Q04760 2/20 0.42
▸ PTGS1 P23219 1/20 0.39
▸ GSTK1 Q9Y2Q3 1/20 0.39
▸ KMT2A Q03164 2/20 0.35
▸ POLB P06746 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ NOD1 Q9Y239 5/20 0.33
▸ LTA4H P09960 1/20 0.32
▸ CTSS P25774 1/20 0.32
▸ CTSK P43235 1/20 0.32
▸ CAPN1 P07384 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23446454 0.96 GLO1 (0.39) GLO1PTGS1GSTK1KMT2APOLB
SCHEMBL24235726 0.93 GLO1 (0.38) GLO1PTGS1GSTK1KMT2APOLB
SCHEMBL23446816 0.90 KMT2A (0.42) GLO1PTGS1GSTK1KMT2APOLB
SCHEMBL24235778 0.86 GLP1R (0.43) KMT2ANOD1CAPN1
SCHEMBL7257742 0.85 L3MBTL1 (0.38) KMT2APOLBL3MBTL1LTA4HCTSS
SCHEMBL24235578 0.84 L3MBTL1 (0.32) GLO1PTGS1GSTK1KMT2APOLB
SCHEMBL9688654 0.83 KMT2A (0.43) GLO1PTGS1GSTK1KMT2APOLB
SCHEMBL10421162 0.83 KMT2A (0.43) GLO1PTGS1GSTK1KMT2APOLB
SCHEMBL9689060 0.83 KMT2A (0.43) GLO1PTGS1GSTK1KMT2APOLB
SCHEMBL9689026 0.83 KMT2A (0.43) GLO1PTGS1GSTK1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11793881-B2 Polyethylene glycol conjugate medicament, preparation method therefor and use thereof Chongqing Upgra Biotechnology Co., Ltd. (CN) 2023-10-24 — — US disclosed
WO-2022022360-A1 POLYETHYLENE GLYCOL CONJUGATE DRUG, AND PREPARATION METHOD THERFOR AND USE THEREOF 重庆阿普格雷生物科技有限公司 2022-02-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11793881-B2 Polyethylene glycol conjugate medicament, preparation method therefor and use thereof SLC10A1, SLC10A2, NOTUM GLO1 1337/4885PTGS1 678/4885GSTK1 2348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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