SCHEMBL24236271

SCHEMBL24236271

CC1(C)c2cc(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)ccc2-c2cc3ccc(N(c4ccccc4)c4ccccc4)cc3cc21

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 14/20 0.36
RARA P10276 2/20 0.34
RARB P10826 2/20 0.34
RARG P13631 2/20 0.34
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
LPL P06858 1/20 0.31
LIPG Q9Y5X9 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23598214 0.99 PDK2 (0.38) PDK2RARARARBRARGKDM4E
SCHEMBL16139457 0.96 PDK2 (0.34) PDK2RARARARBRARGKDM4E
SCHEMBL24236272 0.95 RARA (0.36) PDK2RARARARBRARGKDM4E
SCHEMBL24236289 0.95 PDK2 (0.35) PDK2RARARARBRARGKDM4E
SCHEMBL24236184 0.93 PDK2 (0.34) PDK2RARARARBRARGKDM4E
SCHEMBL24406412 0.92 PDK2 (0.39) PDK2KDM4EALDH1A1CYP1A2CYP3A4
SCHEMBL24343419 0.92 LPL (0.39) PDK2RARARARBRARGKDM4E
SCHEMBL13658662 0.92 LPL (0.38) PDK2KDM4EALDH1A1CYP1A2CYP3A4
SCHEMBL12954417 0.92 ALDH1A1 (0.35) PDK2RARARARBRARGKDM4E
SCHEMBL18353785 0.92 PDK2 (0.38) PDK2KDM4EALDH1A1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220140247-A1 PLURALITY OF HOST MATERIALS, COMPOSITION COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-05-05 US disclosed
US-20220037596-A1 PLURALITY OF LIGHT-EMITTING MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2022-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220037596-A1 PLURALITY OF LIGHT-EMITTING MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, EML4, NECTIN4 PDK2 1625/4885RARA 1215/4885RARB 1956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.