Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24667866 | 0.82 | CASR (0.36) | HTR6 | |
| SCHEMBL19268883 | 0.82 | MAPT (0.37) | MAPTMAPK1TDP1HTR6TSHR | |
| SCHEMBL24667548 | 0.81 | SIGMAR1 (0.30) | — | |
| SCHEMBL21215259 | 0.80 | CSNK2A2 (0.34) | HTR6 | |
| SCHEMBL24305760 | 0.77 | HTR6 (0.34) | HTR6HSD17B10 | |
| SCHEMBL20861097 | 0.76 | MAPT (0.34) | KDM4EMAPTMAPK1L3MBTL1HTR6 | |
| SCHEMBL21077287 | 0.75 | DYRK1A (0.35) | — | |
| SCHEMBL20118736 | 0.72 | — | — | |
| SCHEMBL13338392 | 0.70 | MEN1 (0.45) | KDM4EMAPTMAPK1TDP1NPSR1 | |
| SCHEMBL21085326 | 0.69 | CCNA2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11877506-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2024-01-16 | — | — | US | disclosed |
| US-20220037591-A1 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2022-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11877506-B2 | Polycyclic aromatic compound | F11, C1R, RNF31 | KDM4E 4253/4885MAPT 4416/4885RAD52 2068/4885 |
| US-20220037591-A1 | Polycyclic aromatic compound | F11, C1R, RNF31 | KDM4E 4253/4885MAPT 4416/4885RAD52 2068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.