Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24294564 | 0.90 | LMNA (0.47) | LMNASMN1; SMN2L3MBTL1MAPTLGALS8 | |
| SCHEMBL17283437 | 0.80 | MAPK1 (0.42) | LMNASMN1; SMN2L3MBTL1LGALS8HTT | |
| SCHEMBL24294567 | 0.80 | LMNA (0.43) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL24239904 | 0.77 | LMNA (0.52) | LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL23777371 | 0.77 | LMNA (0.40) | LMNASMN1; SMN2L3MBTL1MAPTCYP3A4 | |
| SCHEMBL30980624 | 0.73 | MAPK1 (0.52) | LMNASMN1; SMN2LGALS8MEN1KMT2A | |
| SCHEMBL18875834 | 0.73 | TGM2 (0.40) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL18875836 | 0.73 | TGM2 (0.40) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL7064868 | 0.73 | LGALS8 (0.42) | LGALS8ALDH1A1TSHR | |
| SCHEMBL23777341 | 0.73 | MAPK1 (0.41) | LGALS8ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220031847-A1 | THERAPEUTIC METHODS | GENEVANT SCIENCES GMBH (CH) | 2022-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220031847-A1 | THERAPEUTIC METHODS | NUP205, HNRNPH3, FUS | LMNA 64/4885SMN1; SMN2 358/4885L3MBTL1 277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.