Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25452139 | 0.81 | GRM2 (0.40) | ALDH1A1HTR3EHTR3BHTR1DHTR2C | |
| SCHEMBL25094185 | 0.80 | NOTUM (0.42) | ALDH1A1HTR3EHTR3BHTR1DHTR2C | |
| SCHEMBL25675637 | 0.80 | ACACB (0.39) | ALDH1A1HTR2CMAPTACACBHRH3 | |
| SCHEMBL24243037 | 0.77 | CHRNB4 (0.42) | ALDH1A1HTR3EHTR3BHTR1DHTR2C | |
| SCHEMBL30493024 | 0.75 | DDB1 (0.49) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL24123765 | 0.74 | HRH3 (0.38) | ALDH1A1HTR1DHTR2CHTR3AMAPT | |
| SCHEMBL12017183 | 0.74 | ALDH1A1 (0.49) | ALDH1A1HTR3EHTR3BHTR1DHTR2C | |
| SCHEMBL20096221 | 0.74 | NOTUM (0.54) | ALDH1A1HTR3EHTR3BHTR1DHTR2C | |
| SCHEMBL20095964 | 0.74 | NOTUM (0.54) | ALDH1A1HTR3EHTR3BHTR1DHTR2C | |
| SCHEMBL14349176 | 0.73 | ALDH1A1 (0.45) | ALDH1A1HTR3EHTR3BHTR1DHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220041597-A1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X | FORMA THERAPEUTICS, INC. | 2022-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220041597-A1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X | MCL1, HSPA9, USP10 | ALDH1A1 3803/4885HTR3E 2906/4885HTR3B 3967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.