Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.47 |
| ▸ | CA2 | P00918 | 11/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 8/20 | 0.35 |
| ▸ | CA9 | Q16790 | 6/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.35 |
| ▸ | CA5A | P35218 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24393341 | 0.72 | CA1 (0.52) | CA1CA2PPARACA12CA9 | |
| SCHEMBL10639327 | 0.72 | THRB (0.35) | — | |
| SCHEMBL966015 | 0.72 | CA1 (0.50) | CA1CA2PPARACA12CA9 | |
| SCHEMBL20782523 | 0.71 | CA1 (0.56) | CA1CA2PPARACA12CA9 | |
| SCHEMBL16633241 | 0.71 | ALDH1A1 (0.54) | — | |
| SCHEMBL9958207 | 0.71 | THRB (0.38) | — | |
| SCHEMBL8079379 | 0.71 | POLB (0.37) | CA1CA2PPARACA12CA14 | |
| SCHEMBL9137387 | 0.69 | EPHX1 (0.33) | CA1CA2CA12CA14CA7 | |
| SCHEMBL10036684 | 0.69 | THRB (0.36) | — | |
| SCHEMBL20079219 | 0.68 | CA1 (0.46) | CA1CA2PPARACA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374802-B1 | KYNURENINE PRODUCTION INHIBITOR | KYOWA HAKKO KIRIN CO LTD (JP) | 2014-04-23 | — | — | EP | disclosed |
| US-8673908-B2 | Kynurenine production inhibitor | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2014-03-18 | — | — | US | disclosed |
| EP-2374802-A1 | KYNURENINE PRODUCTION INHIBITOR | Kyowa Hakko Kirin Co., Ltd. (JP) | 2011-10-12 | — | — | EP | disclosed |
| US-20110237584-A1 | KYNURENINE PRODUCTION INHIBITOR | KYOWA KIRIN CO., LTD. (JP) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237584-A1 | KYNURENINE PRODUCTION INHIBITOR | KYNU, KMO, IDO1 | CA1 2030/4885CA2 2660/4885PPARA 1626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.