Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | GRM5 | P41594 | 4/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24251459 | 0.88 | SPR (0.42) | SPRP2RX7GRM5MAPK14ALDH1A1 | |
| SCHEMBL24251587 | 0.85 | HPGD (0.44) | ALDH1A1HPGDKDM4EHCRTR1HCRTR2 | |
| SCHEMBL24251560 | 0.82 | MYT1 (0.38) | P2RX7GRM5HCRTR1HCRTR2 | |
| SCHEMBL24251549 | 0.82 | SPR (0.36) | SPRPDE4BPDE4DHCRTR1HCRTR2 | |
| SCHEMBL24251406 | 0.81 | SPR (0.41) | SPRPDE4BPDE4DP2RX7GRM5 | |
| SCHEMBL24251391 | 0.81 | CYP3A4 (0.37) | SPRALDH1A1HPGDHCRTR1HCRTR2 | |
| SCHEMBL24251483 | 0.81 | P2RX7 (0.53) | SPRP2RX7 | |
| SCHEMBL24251579 | 0.80 | PDE4B (0.42) | SPRPDE4BPDE4DALDH1A1HPGD | |
| SCHEMBL24251385 | 0.80 | SPR (0.40) | SPRMAPK14ALDH1A1HPGDKDM4E | |
| SCHEMBL23355438 | 0.78 | PDE4B (0.35) | PDE4BPDE4DALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048903-A1 | Anthelminthic Heterocyclic Compounds | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048903-A1 | Anthelminthic Heterocyclic Compounds | SDHA, PAH, PIGS | SPR 4545/4885PARP1 4873/4885PDE4B 2415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.