Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 5/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | APOB | P04114 | 2/20 | 0.35 |
| ▸ | MTTP | P55157 | 2/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24251550 | 0.90 | PDE2A (0.42) | PDE10APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24251414 | 0.87 | HSD17B2 (0.38) | SCN9ASCN5A | |
| SCHEMBL24251390 | 0.86 | PDE10A (0.43) | PDE10AWDR5SCN9A | |
| SCHEMBL24251594 | 0.81 | HSD17B2 (0.40) | CYP11B1CYP11B2CCR2 | |
| SCHEMBL24251444 | 0.78 | TAS1R3 (0.44) | PDE10A | |
| SCHEMBL24251441 | 0.77 | PDE2A (0.42) | PDE10APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24251543 | 0.77 | PDE10A (0.45) | PDE10AWDR5 | |
| SCHEMBL24251374 | 0.77 | TAS1R3 (0.49) | PDE10A | |
| SCHEMBL24251504 | 0.76 | PDE10A (0.37) | PDE10APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24251396 | 0.73 | TAS1R3 (0.48) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048903-A1 | Anthelminthic Heterocyclic Compounds | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048903-A1 | Anthelminthic Heterocyclic Compounds | SDHA, PAH, PIGS | PDE10A 1700/4885PDE4A 3002/4885PDE4B 2415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.