Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24496623 | 0.83 | CCNA2 (0.32) | CYP1A2CYP2C9TSHRCYP2C19GRM1 | |
| SCHEMBL24251705 | 0.83 | CCNA2 (0.33) | CYP1A2CYP2C9TSHRCYP2C19GRM1 | |
| SCHEMBL20680456 | 0.82 | CCNA2 (0.34) | CYP1A2CYP2C9TSHRCYP2C19GRM1 | |
| SCHEMBL29598023 | 0.82 | CCNA2 (0.34) | CYP1A2CYP2C9TSHRCYP2C19GRM1 | |
| SCHEMBL1642783 | 0.77 | LMNA (0.38) | TSHRALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL24251663 | 0.76 | LMNA (0.39) | KDM4EGAA | |
| SCHEMBL24496571 | 0.75 | CYP1A2 (0.36) | CYP1A2CYP2C9TSHRCYP2C19 | |
| SCHEMBL24251774 | 0.74 | IAPP (0.43) | CYP1A2CYP2C9TSHRCYP2C19CCNA2 | |
| SCHEMBL13947192 | 0.74 | IDO1 (0.39) | ALDH1A1KDM4EGAASMN1; SMN2MAPT | |
| SCHEMBL13044666 | 0.72 | ESR1 (0.44) | TSHRALDH1A1KDM4EGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4257584-A1 | 2,3-DIHYDRO-1H-PYRROLO[3,2-B]PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2023-10-11 | — | — | EP | disclosed |
| WO-2023011505-A1 | PYRIMIDINE OR PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN PHARMACY | 上海和誉生物医药科技有限公司 | 2023-02-09 | — | — | WO | disclosed |
| WO-2022116995-A1 | 2,3-DIHYDRO-1H-PYRROLO[3,2-B]PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海和誉生物医药科技有限公司 | 2022-06-09 | — | — | WO | disclosed |
| WO-2022033455-A1 | TRIAZINE DERIVATIVE HAVING EGFR INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海和誉生物医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |