Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24251776 | 0.84 | IAPP (0.45) | IAPPSMN1; SMN2MAPTMAPK1TP53 | |
| SCHEMBL24251705 | 0.77 | CCNA2 (0.33) | SMN1; SMN2CYP1A2CYP2C9CYP2C19RAB9A | |
| SCHEMBL24251664 | 0.74 | CYP1A2 (0.37) | SMN1; SMN2MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL24496623 | 0.74 | CCNA2 (0.32) | CYP1A2CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL1161278 | 0.71 | MAPT (0.48) | SMN1; SMN2MAPTMAPK1TP53CYP1A2 | |
| SCHEMBL24251663 | 0.71 | LMNA (0.39) | NPC1RAB9AKDM4ELMNAHSD17B10 | |
| SCHEMBL9089861 | 0.70 | MAPK1 (0.44) | IAPPSMN1; SMN2MAPTMAPK1TP53 | |
| SCHEMBL23554282 | 0.70 | MAPT (0.55) | SMN1; SMN2MAPTMAPK1TP53CYP1A2 | |
| SCHEMBL16372000 | 0.70 | LCK (0.47) | SMN1; SMN2MAPTMAPK1TP53CYP1A2 | |
| SCHEMBL29549633 | 0.70 | MAPT (0.55) | SMN1; SMN2MAPTMAPK1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022033455-A1 | TRIAZINE DERIVATIVE HAVING EGFR INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海和誉生物医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |