Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 17/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29392101 | 1.00 | TXNRD1 (0.44) | TXNRD1ALDH1A1GSRGSTP1GSTM2 | |
| SCHEMBL9524102 | 0.92 | TXNRD1 (0.51) | TXNRD1ALDH1A1GSRMAPTMAPK1 | |
| SCHEMBL24496404 | 0.87 | ALDH1A1 (0.43) | ALDH1A1GSTP1GSTM2LMNAMAPT | |
| SCHEMBL3961361 | 0.85 | KMT2A (0.44) | TXNRD1ALDH1A1GSRGSTP1GSTM2 | |
| SCHEMBL30937582 | 0.83 | ALDH1A1 (0.60) | TXNRD1ALDH1A1GSRMAPTMAPK1 | |
| SCHEMBL14333655 | 0.81 | ALDH1A1 (0.46) | TXNRD1ALDH1A1GSRGSTP1GSTM2 | |
| SCHEMBL20066169 | 0.80 | TXNRD1 (0.49) | TXNRD1ALDH1A1GSRMAPTMAPK1 | |
| SCHEMBL31292368 | 0.80 | LMNA (0.41) | TXNRD1ALDH1A1GSTP1GSTM2LMNA | |
| SCHEMBL31347036 | 0.80 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTMAPK1KMT2A | |
| SCHEMBL24496548 | 0.80 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115836064-A | Triazine derivative with EGFR (epidermal growth factor receptor) inhibitory activity and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-03-21 | — | — | CN | disclosed |
| WO-2022033455-A1 | TRIAZINE DERIVATIVE HAVING EGFR INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海和誉生物医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |