Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.35 |
| ▸ | HPGD | P15428 | 7/20 | 0.35 |
| ▸ | GLA | P06280 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 8/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23465518 | 0.77 | DYRK1A (0.36) | DYRK1AALDH1A1KDM4EHPGDGLA | |
| SCHEMBL25092575 | 0.77 | ALDH1A1 (0.39) | DYRK1AALDH1A1KDM4EHPGDGLA | |
| SCHEMBL25092440 | 0.77 | DYRK1A (0.33) | DYRK1AALDH1A1KDM4EHPGDGLA | |
| SCHEMBL24874238 | 0.74 | KDM4E (0.32) | DYRK1AALDH1A1KDM4EHPGDGLA | |
| SCHEMBL24253538 | 0.73 | KDM4E (0.33) | DYRK1AALDH1A1KDM4EHPGDGLA | |
| SCHEMBL15688379 | 0.69 | ALDH1A1 (0.39) | DYRK1AALDH1A1KDM4EHPGDGLA | |
| SCHEMBL25064768 | 0.67 | KDM4E (0.32) | DYRK1AALDH1A1KDM4EHPGDGLA | |
| SCHEMBL24253459 | 0.66 | KDM4E (0.33) | DYRK1AALDH1A1KDM4EHPGDGLA | |
| SCHEMBL22448220 | 0.64 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL259600 | 0.64 | ALDH1A1 (0.41) | DYRK1AALDH1A1KDM4EHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048890-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048890-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | RBM17, SF3B1, SF3B5 | DYRK1A 4465/4885ALDH1A1 3964/4885KDM4E 2544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.