SCHEMBL24253891

SCHEMBL24253891

c1ccc(-c2ccc(N3c4ccccc4-c4cccc5c(-c6cccc(-c7nc(-c8ccccc8)nc(-c8ccccc8)n7)c6)ccc(c45)-c4ccccc43)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.43
MGLL Q99685 2/20 0.34
FAAH O00519 1/20 0.34
ALDH1A1 P00352 6/20 0.33
KDM4E B2RXH2 5/20 0.33
KMT2A Q03164 5/20 0.33
MAPT P10636 4/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
USP2 O75604 2/20 0.33
HTT P42858 1/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
TDP1 Q9NUW8 3/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
POLB P06746 2/20 0.33
RECQL P46063 2/20 0.33
CASP6 P55212 2/20 0.33
APEX1 P27695 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24253979 0.95 ALDH1A1 (0.37) PDE6DMGLLALDH1A1KDM4EKMT2A
SCHEMBL24253893 0.91 PDE6D (0.46) PDE6DMGLLFAAHALDH1A1KDM4E
SCHEMBL24254015 0.90 PDE6D (0.38) PDE6DMGLLFAAHALDH1A1KDM4E
SCHEMBL24254018 0.90 HSP90AA1 (0.36) PDE6DMGLLALDH1A1KDM4EKMT2A
SCHEMBL24254014 0.89 PDE6D (0.43) PDE6DMGLLFAAHALDH1A1KDM4E
SCHEMBL24254125 0.87 PDE6D (0.38) PDE6DMGLLALDH1A1KDM4EKMT2A
SCHEMBL18878310 0.86 ALDH1A1 (0.42) ALDH1A1KDM4EKMT2AMAPTSMN1; SMN2
SCHEMBL18878323 0.86 ALDH1A1 (0.42) ALDH1A1KDM4EKMT2AMAPTSMN1; SMN2
SCHEMBL24253892 0.85 PDE6D (0.37) PDE6DMGLLFAAHALDH1A1KDM4E
SCHEMBL24254093 0.85 PDE6D (0.41) PDE6DMGLLALDH1A1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220052272-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220052272-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TMEM109, OR10J3, LEF1 PDE6D 755/4885MGLL 1178/4885FAAH 3668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.