SCHEMBL24254015

SCHEMBL24254015

c1ccc(-c2cccc(-c3nc(-c4ccccc4)nc(-c4ccc5c6c(cccc46)-c4ccccc4N(c4ccccc4)c4ccccc4-5)n3)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.38
ALDH1A1 P00352 3/20 0.36
HTT P42858 2/20 0.36
KDM4E B2RXH2 2/20 0.36
USP2 O75604 2/20 0.36
KMT2A Q03164 2/20 0.36
MAPT P10636 1/20 0.36
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MGLL Q99685 2/20 0.35
FAAH O00519 1/20 0.35
HSP90AA1 P07900 1/20 0.35
PKM P14618 1/20 0.35
ATM Q13315 1/20 0.35
POLB P06746 1/20 0.34
APOBEC3A P31941 1/20 0.34
RECQL P46063 1/20 0.34
CASP6 P55212 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24254014 0.94 PDE6D (0.43) PDE6DALDH1A1HTTKDM4EUSP2
SCHEMBL24253979 0.93 ALDH1A1 (0.37) PDE6DALDH1A1HTTKDM4EUSP2
SCHEMBL24253893 0.91 PDE6D (0.46) PDE6DALDH1A1HTTKDM4EUSP2
SCHEMBL24253891 0.90 PDE6D (0.43) PDE6DALDH1A1HTTKDM4EUSP2
SCHEMBL24253892 0.90 PDE6D (0.37) PDE6DALDH1A1HTTKDM4EMAPT
SCHEMBL26165276 0.87 PDE6D (0.40) PDE6DALDH1A1HTTKDM4EUSP2
SCHEMBL24254093 0.85 PDE6D (0.41) PDE6DALDH1A1KDM4EKMT2AMAPT
SCHEMBL26165279 0.83 PDE6D (0.38) PDE6DALDH1A1KDM4EKMT2AMAPT
SCHEMBL16884769 0.83 MEN1 (0.41) PDE6DALDH1A1HTTKDM4EKMT2A
SCHEMBL16884770 0.83 MEN1 (0.41) PDE6DALDH1A1HTTKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220052272-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220052272-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TMEM109, OR10J3, LEF1 PDE6D 755/4885ALDH1A1 103/4885HTT 4520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.