Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4401844 | 0.84 | KMT2A (0.56) | ALDH1A1MAPTLMNAGAANPSR1 | |
| SCHEMBL2428512 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAPTGAAMAPK1KMT2A | |
| SCHEMBL5474962 | 0.81 | MEN1 (0.56) | ALDH1A1MAPTGAANPSR1POLB | |
| SCHEMBL5100819 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAGAAPOLB | |
| SCHEMBL1070964 | 0.80 | ALDH1A1 (0.60) | ALDH1A1MAPTLMNAGAANPSR1 | |
| SCHEMBL4392250 | 0.80 | KMT2A (0.54) | ALDH1A1MAPTLMNAGAANPSR1 | |
| SCHEMBL4396662 | 0.80 | KMT2A (0.54) | ALDH1A1MAPTLMNAGAANPSR1 | |
| SCHEMBL5097622 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAGAAPOLB | |
| SCHEMBL1258720 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAGAANPSR1 | |
| SCHEMBL8399573 | 0.78 | GPR119 (0.53) | LMNAMAPK1IDO1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263550-A1 | THERAPEUTIC AGENT FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-10-27 | — | — | US | disclosed |
| US-8012971-B2 | Therapeutic agent for chronic obstructive pulmonary disease | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-20090131439-A1 | Therapeutic agent for chronic obstructive pulmonary disease | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2009-05-21 | — | — | US | disclosed |
| EP-1875915-A1 | THERAPEUTIC AGENT FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131439-A1 | Therapeutic agent for chronic obstructive pulmonary disease | CFTR, SCLY, ELANE | ALDH1A1 2234/4885MAPT 4707/4885LMNA 3281/4885 |
| US-20110263550-A1 | THERAPEUTIC AGENT FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE | CFTR, SCLY, ELANE | ALDH1A1 2234/4885MAPT 4707/4885LMNA 3281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.