Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1011860 | 0.80 | KMT2A (0.44) | ALDH1A1MAPTLMNAGAAKMT2A | |
| SCHEMBL2425405 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNAGAAKMT2A | |
| SCHEMBL5443637 | 0.79 | IDO1 (0.69) | ALDH1A1MAPTLMNAGAAKMT2A | |
| SCHEMBL16480211 | 0.79 | RAB9A (0.65) | MAPTLMNAGAAKMT2AMEN1 | |
| SCHEMBL15074689 | 0.77 | GAA (0.58) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL25633561 | 0.75 | IDO1 (0.79) | ALDH1A1MAPTLMNAGAAKMT2A | |
| SCHEMBL28259440 | 0.75 | ALDH1A1 (1.00) | ALDH1A1MAPTLMNAGAAKMT2A | |
| SCHEMBL18330292 | 0.74 | MAPT (0.63) | ALDH1A1MAPTLMNAGAAKMT2A | |
| SCHEMBL12411794 | 0.73 | MEN1 (0.62) | MAPTGAAKMT2AMEN1HPGD | |
| SCHEMBL19277750 | 0.73 | GAA (1.00) | ALDH1A1MAPTLMNAGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110039848-A1 | FIVE-MEMBERED RING COMPOUND | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-02-17 | — | — | US | disclosed |
| US-20110034466-A1 | NOVEL FIVE-MEMBERED RING COMPOUND | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-02-10 | — | — | US | disclosed |
| EP-2272844-A1 | FIVE-MEMBERED RING COMPOUND | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2011-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034466-A1 | NOVEL FIVE-MEMBERED RING COMPOUND | CCL11, CCR1, CCR10 | ALDH1A1 2564/4885MAPT 4799/4885LMNA 4342/4885 |
| US-20110039848-A1 | FIVE-MEMBERED RING COMPOUND | IL5, EPX, CCL11 | ALDH1A1 2744/4885MAPT 4510/4885LMNA 4443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.