Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 19/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24253982 | 0.86 | TNIK (0.39) | TNIK | |
| SCHEMBL24253785 | 0.81 | TNIK (0.60) | TNIK | |
| SCHEMBL21247884 | 0.73 | TNIK (1.00) | TNIK | |
| SCHEMBL24253983 | 0.71 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL24253815 | 0.70 | TNIK (0.60) | TNIK | |
| SCHEMBL22978321 | 0.70 | TNIK (0.70) | TNIK | |
| SCHEMBL24253788 | 0.68 | GPR119 (0.41) | TNIK | |
| SCHEMBL24253879 | 0.68 | TNIK (0.60) | TNIK | |
| SCHEMBL22978358 | 0.67 | TNIK (0.74) | TNIK | |
| SCHEMBL29965615 | 0.67 | TNIK (0.74) | TNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022034587-A1 | Traf2- AND Nck-INTERACTING KINASE (TNIK) INHIBITORS AND USES THEREOF | TNIK THERAPEUTICS LTD (IL) | 2022-02-17 | — | — | WO | disclosed |