Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 9/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.32 |
| ▸ | GPR4 | P46093 | 1/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24254072 | 0.86 | TNIK (0.56) | TNIK | |
| SCHEMBL24253788 | 0.83 | GPR119 (0.41) | TNIKGPR119PIK3CD | |
| SCHEMBL24253983 | 0.69 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL24253785 | 0.67 | TNIK (0.60) | TNIK | |
| SCHEMBL24253816 | 0.66 | GPR119 (0.46) | GPR119PIK3CDTBK1 | |
| SCHEMBL4936482 | 0.61 | GPR119 (0.65) | GPR119PIK3CD | |
| SCHEMBL24254068 | 0.60 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL21247730 | 0.59 | TNIK (0.48) | TNIKGPR119PIK3CD | |
| SCHEMBL4808991 | 0.59 | ALOX15 (0.42) | GPR119 | |
| SCHEMBL4808986 | 0.59 | GPR119 (0.43) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022034587-A1 | Traf2- AND Nck-INTERACTING KINASE (TNIK) INHIBITORS AND USES THEREOF | TNIK THERAPEUTICS LTD (IL) | 2022-02-17 | — | — | WO | disclosed |