Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | GALR3 | O60755 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11400978 | 0.83 | HPGD (0.54) | HPGDALDH1A1HSP90AA1THRBSMN1; SMN2 | |
| SCHEMBL1163831 | 0.83 | THRB (0.56) | HPGDALDH1A1HSP90AA1THRBSMN1; SMN2 | |
| SCHEMBL5517767 | 0.83 | HPGD (0.54) | HPGDALDH1A1HSP90AA1THRBSMN1; SMN2 | |
| SCHEMBL5509693 | 0.82 | THRB (0.51) | HPGDALDH1A1HSP90AA1THRBSMN1; SMN2 | |
| SCHEMBL23613828 | 0.79 | HPGD (0.51) | HPGDALDH1A1HSP90AA1THRBSMN1; SMN2 | |
| SCHEMBL5509510 | 0.78 | LMNA (0.56) | HPGDALDH1A1HSP90AA1THRBSMN1; SMN2 | |
| SCHEMBL3158236 | 0.78 | SMN1; SMN2 (0.58) | HPGDALDH1A1THRBSMN1; SMN2LMNA | |
| SCHEMBL620433 | 0.78 | THRB (0.51) | HPGDALDH1A1HSP90AA1THRBSMN1; SMN2 | |
| SCHEMBL26010796 | 0.77 | LMNA (0.62) | HPGDALDH1A1THRBSMN1; SMN2LMNA | |
| SCHEMBL11394808 | 0.76 | TSHR (0.50) | HPGDALDH1A1HSP90AA1THRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196108-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | The Trustees of Indiana University (US) | 2023-06-21 | — | — | EP | claimed |
| WO-2022036282-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2022-02-17 | — | — | WO | claimed |
| US-20230257373-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH | 2023-08-17 | — | — | US | disclosed |
| US-20230257373-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH | 2023-08-17 | — | — | US | disclosed |
| EP-4196108-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | The Trustees of Indiana University (US) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022036282-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2022-02-17 | — | — | WO | disclosed |
| WO-2022036282-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2022-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257373-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | PGLS, BLVRB, CGAS | HPGD 1909/4885ALDH1A1 4358/4885HSP90AA1 2301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.