Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR27 | Q9NS67 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24254503 | 0.81 | MGAT2 (0.54) | GPR27MGAT2MEN1KMT2A | |
| SCHEMBL24254519 | 0.77 | MGAT2 (0.57) | GPR27MGAT2MEN1KMT2A | |
| SCHEMBL24254494 | 0.77 | EPHX2 (0.55) | PPARG | |
| SCHEMBL26188116 | 0.74 | EPHX2 (0.61) | PPARGMEN1KMT2A | |
| SCHEMBL24254499 | 0.74 | LMNA (0.53) | MEN1KMT2A | |
| SCHEMBL6762119 | 0.69 | TMPRSS6 (0.57) | MGAT2 | |
| SCHEMBL26188045 | 0.68 | ALDH1A1 (0.57) | MEN1KMT2A | |
| SCHEMBL24254491 | 0.68 | ALDH1A1 (0.52) | MEN1KMT2A | |
| SCHEMBL24254488 | 0.68 | KMT2A (0.58) | MEN1KMT2A | |
| SCHEMBL26188352 | 0.68 | PKM (0.50) | GPR27MGAT2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035804-A1 | SUBSTITUTED 3-AMINO-4-METHYLBENZENESULFONAMIDES AS SMALL MOLECULE INHIBITORS OF UBIQUITIN-SPECIFIC PROTEASE 28 | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-02-17 | — | — | WO | disclosed |