Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 8/20 | 0.54 |
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14516217 | 0.81 | F2 (0.59) | F2NPC1RAB9APOLBKMT2A | |
| SCHEMBL27820687 | 0.81 | MMP8 (0.62) | NPC1RAB9APOLBKMT2AS1PR1 | |
| SCHEMBL11181798 | 0.76 | KMT2A (0.61) | F2NPC1RAB9APOLBKMT2A | |
| SCHEMBL12502132 | 0.75 | F2 (1.00) | F2NPC1RAB9AKMT2ANPSR1 | |
| SCHEMBL1042666 | 0.75 | ALDH1A1 (0.56) | NPC1RAB9AKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL1565503 | 0.75 | F2 (0.51) | F2NPC1RAB9APOLBKMT2A | |
| SCHEMBL2899163 | 0.74 | NR3C1 (0.67) | F2NPC1RAB9APOLBKMT2A | |
| SCHEMBL4247770 | 0.74 | POLB (0.66) | NPC1RAB9APOLBKMT2ASMN1; SMN2 | |
| SCHEMBL28475782 | 0.72 | F2 (0.69) | F2NPC1RAB9APOLBKMT2A | |
| SCHEMBL1565310 | 0.72 | ALDH1A1 (0.65) | F2NPC1RAB9APOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022036033-A2 | SOLID STATE FORMS OF AN ORGANIC COMPOUND | SERVIER PHARMACEUTICALS, LLC (US) | 2022-02-17 | — | — | WO | disclosed |