Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24254531 | 0.82 | KCNQ2 (0.55) | KCNQ2HTTNPC1GAAMAPT | |
| SCHEMBL24254575 | 0.79 | MAPT (0.53) | KCNQ2HTTLMNAGAAMCOLN3 | |
| SCHEMBL24254585 | 0.79 | HTT (0.74) | HTTNPC1LMNAGAAMAPT | |
| SCHEMBL24254507 | 0.76 | MEN1 (0.48) | KCNQ2HTTLMNAGAAMCOLN3 | |
| SCHEMBL24254550 | 0.75 | HPGD (0.46) | KCNQ2HTTNPC1LMNAGAA | |
| SCHEMBL24254512 | 0.74 | HTT (0.76) | HTTNPC1LMNAGAAMAPT | |
| SCHEMBL26188045 | 0.72 | ALDH1A1 (0.57) | HTTNPC1LMNAGAAMAPT | |
| SCHEMBL24254502 | 0.70 | ALDH1A1 (0.66) | HTTLMNAGAAMAPTMEN1 | |
| SCHEMBL24254515 | 0.68 | MAPT (0.48) | KCNQ2HTTLMNAGAAMCOLN3 | |
| SCHEMBL23978667 | 0.66 | SMN1; SMN2 (0.48) | KCNQ2HTTLMNAGAAMCOLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035804-A1 | SUBSTITUTED 3-AMINO-4-METHYLBENZENESULFONAMIDES AS SMALL MOLECULE INHIBITORS OF UBIQUITIN-SPECIFIC PROTEASE 28 | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-02-17 | — | — | WO | disclosed |