Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6126592 | 0.79 | CES1 (0.54) | ALDH1A1BCHEACHEHDAC8HDAC6 | |
| SCHEMBL1260766 | 0.79 | TBXAS1 (0.50) | TDP1NPC1KEAP1ALDH1A1FKBP1A | |
| SCHEMBL712597 | 0.76 | KEAP1 (0.70) | TDP1KEAP1ALDH1A1FFAR1HDAC2 | |
| SCHEMBL7131839 | 0.76 | NPC1 (0.86) | TDP1NPC1ALDH1A1FKBP1APOLB | |
| SCHEMBL18787369 | 0.75 | FBP1 (0.33) | TSHR | |
| Phenyl Propionic Acid SCHEMBL29619843 | 0.73 | KEAP1 (1.00) | TDP1KEAP1ALDH1A1FFAR1HDAC2 | |
| Phenyl Propionic Acid SCHEMBL13618844 | 0.73 | KEAP1 (1.00) | TDP1KEAP1ALDH1A1FFAR1HDAC2 | |
| SCHEMBL497371 | 0.73 | KEAP1 (0.73) | TDP1NPC1KEAP1ALDH1A1FFAR1 | |
| Phenyl Propionic Acid SCHEMBL3419 | 0.73 | KEAP1 (1.00) | TDP1KEAP1ALDH1A1FFAR1HDAC2 | |
| Phenyl Propionic Acid SCHEMBL27523271 | 0.73 | KEAP1 (1.00) | TDP1KEAP1ALDH1A1FFAR1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011112067-A1 | A HERBAL COMPOSITION HAVING ANTI-OBESITY PROPERTY | UNIVERSITI SAINS MALAYSIA (MY) | 2011-09-15 | — | — | WO | disclosed |