Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | STK4 | Q13043 | 1/20 | 0.39 |
| ▸ | STK3 | Q13188 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29426350 | 1.00 | PIK3CA (0.43) | PIK3CAPIK3CDPIK3CBALDH1A1KDM4E | |
| SCHEMBL22315290 | 0.85 | PIK3CD (0.43) | PIK3CAPIK3CDPIK3CBALDH1A1KDM4E | |
| SCHEMBL24195955 | 0.80 | PIK3CA (0.47) | PIK3CAPIK3CDPIK3CBALDH1A1KDM4E | |
| SCHEMBL20865970 | 0.76 | PIK3CD (0.47) | PIK3CAPIK3CDPIK3CBALDH1A1KDM4E | |
| SCHEMBL746825 | 0.75 | GRM2 (0.51) | — | |
| SCHEMBL747445 | 0.74 | GRM2 (0.49) | — | |
| SCHEMBL27001781 | 0.74 | ALDH3A1 (0.51) | PIK3CAPIK3CDPIK3CBALDH1A1KDM4E | |
| SCHEMBL22385030 | 0.73 | PIK3CD (0.43) | PIK3CAPIK3CDPIK3CBALDH1A1LMNA | |
| SCHEMBL1801712 | 0.72 | SMN1; SMN2 (0.58) | PIK3CAPIK3CDPIK3CBALDH1A1KDM4E | |
| SCHEMBL1536488 | 0.70 | PIK3CD (0.47) | PIK3CAPIK3CDPIK3CBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303513-A1 | OXOPYRROLIDINE UREA FPR2 AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2023-09-28 | — | — | US | disclosed |
| US-20230303513-A1 | OXOPYRROLIDINE UREA FPR2 AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2023-09-28 | — | — | US | disclosed |
| WO-2022035923-A1 | OXOPYRROLIDINE UREA FPR2 AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303513-A1 | OXOPYRROLIDINE UREA FPR2 AGONISTS | FPR1, FPR2, FPR3 | PIK3CA 3769/4885PIK3CD 3732/4885PIK3CB 4422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.